North Carolina Clinical Nurse Specialist License Requirements
Complete guide to becoming a Clinical Nurse Specialist in North Carolina
CNS practice is governed solely by the NC Board of Nursing under 21 NCAC 36 .0228 with no physician collaborative agreement or supervision required (autonomous practice); CNSs have NO pharmacologic prescriptive authority.
Prescriptive Authority: No pharmacologic prescriptive authority. Per 21 NCAC 36 .0228(e), CNSs may prescribe/implement only non-pharmacologic nursing interventions and monitor pharmacologic agents; no medication prescribing or DEA registration.
1 Education Requirements
Degree Required
Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP)
Program Requirements
- Complete accredited Clinical Nurse Specialist program
- Hold active RN license in the state
- Clinical hours as specified by program
2 National Certification
Certification Body
ANCC or AACN
Required
Yes
American Nurses Credentialing Center or American Association of Critical-Care Nurses
3 Fees
Initial Licensure
| Application Fee | $0 |
| Total | $100 |
Renewal
| Renewal Fee (every 2 years) | $50 |
Prerequisites
To become a Clinical Nurse Specialist in North Carolina, you must first hold an active RN license. North Carolina is a member of the Nurse Licensure Compact (NLC), so you may hold a multistate RN license.
State Board of Nursing
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Other APRN Types in North Carolina
Clinically reviewed by Clinical Review Team
Based on 6 official sources • Last verified: July 2026