RN to PA: How Nurses Become Physician Assistants

Considering switching from nursing to physician assistant? This guide covers the path from RN to PA, including prerequisites, how your nursing experience counts, and whether it's the right move for you.

The key question: Before pursuing PA school, carefully consider whether nurse practitioner (NP) might be a better fit. Many RNs find NP offers a shorter path with similar outcomes. This guide will help you decide.

Why Do Nurses Consider Becoming PAs?

Medical Model Training

PA programs follow the medical model, similar to physician training. Some nurses prefer this approach over the nursing model used in NP programs. PA education emphasizes diagnosis and treatment across all specialties before specializing.

Specialty Flexibility

PAs are trained as generalists and can switch specialties throughout their careers without additional certification. NPs must choose a specialty before starting their program and need new certification to change fields.

Standardized Education

PA programs are more standardized than NP programs. All PA students complete similar rotations and graduate with comparable clinical experience. NP program quality and clinical hours vary significantly.

Career Change Desire

Some nurses want to step away from the nursing profession entirely. PA offers a fresh start with a different professional identity while still using clinical skills.

NP vs PA: Side-by-Side Comparison

Before committing to PA school, understand how these careers compare.

Factor
Nurse Practitioner
Physician Assistant
Education Path
BSN → MSN/DNP (2-4 years)
Bachelor's → PA Master's (2-3 years)
Philosophy
Nursing model (holistic care)
Medical model (disease-focused)
Specialty Training
Choose specialty before program
Generalist training, specialize after
Work Experience Required
Often 1-2 years RN experience
1,000-3,000+ hours patient care
Clinical Hours in Program
500-1,000 hours
2,000+ hours
Median Salary
$126,000
$130,000
Autonomy
Varies by state (FPA in 27 states)
Physician supervision required

The Path from RN to PA

1

Earn a Bachelor's Degree

PA programs require a bachelor's degree. If you have a BSN, you're set. If you have an ADN, you'll need to complete a bachelor's degree first—any major works, but science-heavy degrees help with prerequisites.

Time: BSN holders: 0 additional time. ADN holders: 1-2 years for RN-to-BSN or another bachelor's.

2

Complete PA School Prerequisites

PA programs require specific science prerequisites that may not have been part of your nursing education.

Course Credits Notes
Anatomy 3-4 Usually 2 semesters with labs
Physiology 3-4 May be combined with anatomy
Microbiology 3-4 With laboratory
General Chemistry 6-8 2 semesters with labs
Organic Chemistry 3-4 At least 1 semester
Biochemistry 3 Some programs
Statistics 3 Required by most programs
Psychology 3-6 General and/or abnormal
Medical Terminology 1-3 Some programs

Critical: Chemistry requirements trip up many RNs. Most nursing programs don't include organic chemistry or biochemistry. Budget 1-2 years to complete missing prerequisites.

3

Gain Patient Care Experience

This is where RNs have an advantage. PA programs typically require 1,000-3,000+ hours of direct patient care experience. Your RN experience counts.

Good news: Most RNs already exceed the experience requirements. Two years of full-time RN work = 4,000+ patient care hours. This is a major advantage over non-healthcare applicants.

4

Take the GRE

Many PA programs require the Graduate Record Exam (GRE). Some have dropped this requirement, but competitive programs often still require it.

Target scores: 300+ combined (verbal + quantitative), 4.0+ analytical writing. Prepare 2-3 months before testing.

5

Apply Through CASPA

Most PA programs use the Centralized Application Service for Physician Assistants (CASPA). Applications open in late April, and programs have rolling admissions.

Apply early. Many programs fill by late summer. Competitive applicants apply to 8-12 programs.

6

Complete PA Program

PA programs are intensive 24-36 month master's programs with didactic and clinical phases. Clinical rotations cover all major specialties.

Didactic Phase (12-15 months)

  • Anatomy (often with cadaver lab)
  • Physiology
  • Pharmacology
  • Clinical medicine
  • Physical diagnosis

Clinical Phase (12-16 months)

  • Family medicine
  • Internal medicine
  • Surgery
  • Pediatrics
  • Emergency medicine
  • Psychiatry
  • Women's health
7

Pass PANCE and Get Licensed

After graduation, pass the Physician Assistant National Certifying Exam (PANCE) and apply for state licensure.

PANCE is a 300-question, 5-hour exam. National pass rate is approximately 93% for first-time test-takers.

Realistic Timeline: RN to PA

Complete prerequisites (if needed) 1-2 years
Study for and take GRE 2-3 months
Application cycle 6-12 months
PA program 24-36 months
Total Time from RN to PA 3-5 years

Compare to NP: BSN to NP takes 2-4 years, often while working. RN to PA typically requires leaving work for the 2+ year PA program, since most programs don't accommodate working students.

Cost Comparison: NP vs PA Path

NP Path Costs

  • MSN program (2-3 years) $30,000-$80,000
  • Can work while studying Yes (most programs)
  • Net cost (with income) $20,000-$60,000

PA Path Costs

  • Prerequisites (1-2 years) $5,000-$15,000
  • PA program (2-3 years) $80,000-$150,000
  • Lost income (can't work) $140,000-$200,000
  • Total investment $225,000-$365,000

The financial difference is substantial. PA school costs more and typically requires leaving your job. NP programs are often designed for working nurses.

When Does the PA Path Make Sense for RNs?

PA Might Be Right If...

  • You strongly prefer the medical model over nursing model
  • You want flexibility to switch specialties without new certification
  • You're young enough that the longer/costlier path has time to pay off
  • You want to leave nursing entirely for a fresh professional identity
  • You're interested in surgical specialties (more PA opportunities)
  • You have financial resources or support to attend full-time

NP Is Probably Better If...

  • You need to work while completing your education
  • You're concerned about cost and ROI
  • You want to build on your nursing foundation
  • You're interested in independent practice (NP has more autonomy)
  • You already know your desired specialty
  • You want the fastest path to advanced practice